一、基本信息
姓 名:李晨
性 别:男
学历/学位:研究生/理学博士,美国克利夫兰医学中心博士后
职务职称:生物工程系主任,硕士生导师,博士生导师,副教授
所在部门:18luck新利手机版iso 食品科技学院生物工程系(D座1306室,1320室)
通讯地址:河北省保定市乐凯南大街2596号18luck新利手机版iso 食品科技学院生物工程系
邮政编码:071001
联系电话:+86-0312-7528423 (工作)
电子邮箱:lichen@hebau.edu.cn
二、主要学术及社会兼职:
国家自然科学基金函审专家;
中国经济林协会加工利用分会理事;
河北省食品学会青年工作委员会副秘书长;
国内外多家学术期刊审稿专家
九三学社农大二支社副主委
三、学习工作经历
2001.9–2005.6,河北大学,生物技术专业,获学士学位
2006.9–2008.6,南京农业大学,生物化学与分子生物学专业,获硕士学位
2008.9–2011.6,南京农业大学,生物化学与分子生物学专业,获博士学位
2007.9–2011.6,中国农业科学院油料作物研究所,客座研究生
2011.8–至今,18luck新利手机版iso 食品科技学院生物工程系主任、副教授、博士生导师、生物工程与酿酒工程专业负责人
2016.12-2017.9,美国Cleveland Clinic,博士后
四、主讲课程及主要研究方向
1、主讲课程:发酵工程与设备、发酵工艺学、生物制药、微生物学、基因组学与转录组学等本科及研究生课程。
2、主要研究方向:益生菌资源开发利用与功能性食品研究;发酵食品功能性成分分析与人体健康研究;转基因食品安全与风险交流研究。
五、主要研究成果、近年承担的科研项目及获奖情况:
主持项目:
国家自然科学基金(31301520)
河北省自然科学基金(C2016204129)
河北省科技计划项目(12222904)
河北省高等学校科学技术研究项目(ZD2021059;QN2014065)
18luck新利手机版iso 青年科学基金(QJ201221)
参与项目:
国家自然科学基金(31601462)
国家自然科学基金(31501417)
国家自然科学基金(主任基金)(31140065)
国家自然科学基金面上项目(30671312)
国家重大科技专项/重大项目(2019ZX08015002-007)
国家重点研发计划项目子课题(2017YFC1600901)
河北省重点研发计划项目(20327112D;19227134D)
河北省自然科学基金(C2012204099)
河北省科技计划项目(13222806)
中央级公益性科研院所基本科研业务费专项资金(20065049)
湖北省自然科学基金创新群体项目(2008CDA083)
石家庄市科学技术研究与发展计划(11117272A)
发明专利:
申请和授权国家发明专利16项
六、代表性论文
发表论文60余篇,其中SCI/EI收录40余篇,部分代表性论文如下:
[1] Copper inhibits postacidification of yogurt and affects its flavor: A study based on the Cop operon[J]. Journal of Dairy Science, 2023, 106(2):897-911.(Corresponding author)
[2] Effect of fructooligosaccharides on the colonization of Lactobacillus rhamnosus AS1.2466T in the gut of mice. Food Science and Human Wellness, 2023, 12(2):607-613.(Corresponding author)
[3] A novel endophytic bacterial strain improves potato storage characteristics by degrading glycoalkaloids and regulating microbiota. Postharvest Biology and Technology, 2023, 196:112176.(co-first author)
[4] Niacin inhibits post-acidification of yogurt based on the mining of LDB_RS00370 biomarker gene[J]. Food Research International, 2022, 162(Pt A):111929.(Corresponding author)
[5] Mechanism of gastrointestinal adaptability and antioxidant function of infant-derived Lactobacillus plantarum BF_15 through genomics. Food Science and Biotechnology, 2022, 31(11):1451-1462.(Corresponding author)
[6] Global transcriptomic analysis ofLactobacillus delbrueckiisubsp.bulgaricusATCC11842 reveals the role ofLDB_RS05285in the post-acidification of yogurt,Food & Function,Food & Function, 2021, 12(19):9077-9086.(Correspondingauthor)
[7] Probiotics, prebiotics, and synbiotics regulate the intestinal microbiota differentially and restore the relative abundance of specific gut microorganisms, Journal of Dairy Science, 2020, 103: 5816-5829.(first author)
[8] Colonization and immunoregulation of Lactobacillus plantarum BF_15, a novel probiotic strain from the feces of breast-fed infants, Food & Function, 2020, 11:3156-3166.(co-first author)
[9] Food-grade expression of nattokinase in Lactobacillus delbrueckii subsp. bulgaricus and its thrombolytic activity in vitro,BiotechnologyLetters,2020,42:2179–2187.(first author)
[10] Adhesion and Colonization of the Probiotic Lactobacillus rhamnosus Labeled by Dsred2 in Mouse Gut. Current Microbiology, 2019, 76:896-903.(first author)
[11]Induction of telomere-mediated chromosomal truncation and behavior of truncated chromosomes inBrassica napus. The Plant Journal, 2017, 91(4):700-713.(co-first author)
[12] Development of an antibiotic-free plasmid selection system based on thymine auxotrophy inLactococcus lactis. Annals of Microbiology. 2015, 65:1049-1055(first author)
[13] Construction ofLactococcus lactisthyA-null using Red recombination system. Annals of Microbiology. 2013, 63:951-956.(co-first author)
[14] Gene expression profiling ofSinapis albaleaves under drought stress and rewatering growth conditions with Illumina deep sequencing.Molecular Biology Reports. 2012, 39(5):5851-5857.(co-first author)
[15] Large-scale sequencing of normalized full-length cDNA library of soybean seed at different developmental stages and analysis of the gene expression profiles based on ESTs. Molecular Biology Reports. 2012, 39(3):2867-2874.(co-first author)
[16]Cloning, identification and characterization of a repetitive sequence flanking telomere and homologous tocanrepinBrassica napus.Botanical Studies,2010,51: 421-430.(first author)